| Kun-Soo Kim, Ph.D. | |
Office: R217 / Phone: +82-2-705-8460 / E-Mail : kskim@sogang.ac.kr | ||
Molecular Interactions between Bacteria and Eukaryotes MORE > | ||
Research Interests | ||
Molecular interactions between pathogenic bacteria and higher organisms medicated by diffusible signal molecules. Two model systems are currently employed; (1) Interactions between V. vulnificus and human. (2) Interactions between A. tumefaciens and plant. | ||
Selected Publications | ||
Lee BC, Lee JH, Kim MW, Kim BS, Oh MH, Kim KS, Kim TS, Choi SH. Vibrio vulnificus rtxE is important for virulence, and its expression is induced by exposure to host cells. Infect Immun (2008) 76:1509-1517 Goo SY, Lee HJ, Kim WH, Han KL, Park DK, Lee HJ, Kim SM, Kim KS, Lee KH, Park SJ. Identification of OmpU of Vibrio vulnificus as a fibronectin-binding protein and its role in bacterial pathogenesis. Infect Immun (2006) 74: 5586-5594 Park DK, Lee KE, Baek CH, Kim IH, Kwon JH, Lee WK, Lee KH, Kim BS, Choi SH, Kim KS. Cyclo(Phe-Pro) modulates the expression of ompU in Vibrio spp. J Bacteriol (2006) 188:2214-2221 | ||
| Seong-Ryong Kim, Ph.D. | |
Office: R1105 / Phone: +82-2-705-8456 / E-Mail: sungkim@sogang.ac.kr | ||
Plant Molecular Biology Laboratory MORE > | ||
Research Interests | ||
Physiology, biochemistry, and genetics of the stress responsive genes in both plant vegetative and reproductive organs Production of protein biotherapeutics in plants (rice and chlorella) | ||
Selected Publications | ||
Manu Kumar, Ji-Hyeong Jeon, Juyoung Choi, Seong-Ryong Kim* (2018) Rapid and efficient genetic transformation of the green microalga Chlorella vulgaris. J of Applied Phycology 30:1735-1745
Joon-Soo Sim, Mahipal Singh Kesawat, Manu Kumar, Su-Yeon Kim, Vimalraj Mani, Parthiban Subramanian, Soyoung Park, Chang-Muk Lee, Seong-Ryong Kim and Bum-Soo Hahn. Lack of the α1,3-Fucosyltransferase Gene (Osfuct) Affects Anther Development and Pollen Viability in Rice. (2018) Int. J. Mol. Sci. 19:1225; doi:10.3390/ijms1*******
Manu Kumar, Yun-Shil Gho, Ki-Hong Jung, Seong-Ryong Kim* (2017) Genome-wide identification and analysis of genes, conserved between japonica and indica rice cultivars, that respond to low-temperature stress at the vegetative growth stage. Frontiers in Plant Science 8:1120 Sang-Choon Lee, Soo-Jin Kim, Soon-Ki Han, Gynheung An, Seong-Ryong Kim*(2017) A gibberellin-stimulated tran gene, OsGASR1, controls seedling growth and α-amylase expression in rice. J of Plant Physiol. 214:116-122 | ||
| Jungho Kim, Ph.D. | |
Office: R1201 / Phone: +82-2-705-8461 / E-Mail: jkim@sogang.ac.kr | ||
Laboratory for Molecular and Cellular Biology MORE > | ||
Research Interests | ||
Cancer Research Stem Cell Research Cancer Stem Cell Research | ||
Selected Publications | ||
Kim S, Lee HJ, Jun HJ, Kim J. The hTAF II 68-TEC fusion protein functions as a strong transcriptional activator. Int. J. Cancer (2008) 122: 2446-2453 Lee J, Kim JY, Kang IY, Kim HK, Han YM, Kim J. The EWS-Oct-4 fusion gene encodes a transforming gene. Biochem. J. (2007) 406: 519-526 Lee J, Kim HK, Rho JY, Han YM, Kim J. The human OCT-4 isoforms differ in their ability to confer self-renewal. J. Biol. Chem. (2006) 281: 33554-33565 | ||
| Jongchan Kim, Ph.D. | |
Office: R219 / Phone: +82-2-705-7919 / E-Mail: jkimatsgu@sogang.ac.kr | ||
Laboratory of Molecular and Cellular Oncology | ||
Research Interests | ||
Selected Publications | ||
|
Mi Chung Suh, Ph.D. | |
|
Office: R1103 / Phone: +82-2-705-8457 / E-Mail:
mcsuh
@sogang.ac.kr | ||
Plant Molecular Physiology & Biochemistry Laboratory MORE > | ||
Research Interests | ||
Selected Publications | ||
| Hyung-Doo Shin, Ph.D. | |
Office: K327 / Phone: +82-2-705-8615 / E-Mail: hdshin@sogang.ac.kr | ||
Laboratory for Genomic Diversity | ||
Research Interests | ||
Human genetic variation (SNP,CNV) research for personalized medicine Development of epigenetic biomarkers for human disease | ||
Selected Publications | ||
Yasuda K et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nature Genetics (2008) 40:1092-1097 Kim DJ, Choi IG, Park BL, Lee BC, Ham BJ, Yoon S, Bae JS, Cheong HS, Shin HD. Major genetic components underlying alcoholism in Korean population. Human Molecular Genetics (2008) 17: 854-858 Lee JH, Moore JH, Park SW, Jang AS, Uh ST, Kim YH, Park CS, Park BL, Shin HD. Genetic interactions model among Eotaxin gene polymorphisms in asthma. J Hum Genet. (2008) 53:867-875 | ||
| Gap Ryol Lee, Ph.D. | |
Office: R1123 / Phone: +82-2-705-8458 / E-Mail: grlee@sogang.ac.kr | ||
Molecular Immunology Laboratory MORE > | ||
Research Interests | ||
Signal transduction and gene regulation in T helper cells Development of therapeutic strategies to treat allergy and asthma | ||
Selected Publications | ||
Lee GR, Kim ST, Spilianakis CG, Fields PE, Flavell RA. T helper cell differentiation: regulation by cis elements and epigenetics. Immunity (2006) 24: 369-379 Lee GR, Spilianakis CG, Flavell RA. Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions. Nat Immunol. (2005) 6:42-48 Spilianakis CG, Lalioti MD, Town T, Lee GR, Flavell RA. Interchromosomal associations between alternatively expressed loci. Nature (2005) 435: 637-645 | ||
| Kyu-Ho Lee, Ph.D. | |
Office: R205A / Phone: +82-2-705-7963 / E-Mail: kyuholee@sogang.ac.kr | ||
Molecular Microbiology and Biofilm Laboratory MORE > | ||
Research Interests | ||
Biofilm formation by a pathogenic bacterium, Vibrio vulnificus Quorum-sensing regulatory mechanisms in Vibrio vulnificus Host-interacting components of Vibrio vulnificus: Adhesin Transcriptional regulatory networks for pathogenicity of Vibrio vulnificus | ||
Selected Publications | ||
Lee, K.-J., C.-S. Jeong, Y. J. An, H.-J. Lee, S.-J. Park, Y.-J. Seok, P. Kim, J.-H. Lee, K.-H. Lee*, and S.-S. Cha*. 2011. FrsA functions as a cofactor-independent decarboxylase to control metabolic flux. Nature Chemical Biology. 7:434-436. Kim, H.-S., S.-J. Park, and K.-H. Lee. 2009. Role of NtrC-regulated exopolysaccharides in the biofilm formation and pathogenic interaction of Vibrio vulnificus. Molecular Microbiology. 74(2):436-453. Lee, H.-J., S.-J. Park, S. H. Choi, and K.-H. Lee. 2008. Vibrio vulnificus rpoS expression is repressed by direct binding of cAMP-CRP complex to its two promoter regions. Journal of Biological Chemistry. 283(45):30438?30450. | ||
| Byeong-ha Lee, Ph.D. | |
Office: R1107 / Phone: +82-2-705-8794 / E-Mail: byeongha@sogang.ac.kr | ||
Plant Gene Regulation Laboratory MORE > | ||
Research Interests | ||
RNA Processing and Regulation Plant Stress Signaling and Regulation Plant Development Regulation | ||
Selected Publications | ||
https://orcid.org/0000-0001-7633-3264 Yu, S.-i., Kim, H., Yun, D.-J., Suh, M.C., and Lee, B.-h.* (2019) Post-translational and transcriptional regulation of phenylpropanoid biosynthesis pathway by Kelch repeat F-box protein SAGL1. Plant Molecular Biology 99: 135-148. Park, J., Lim, C.J., Shen, M., Park, H.J., Cha, J.-Y., Iniesto, E., Rubio, V., Mengiste, T., Zhu, J.-K., Bressan, R.A., Lee, S.Y., Lee, B.-h., Jin, J.B., Pardo, J.M., Kim, W.Y., and Yun, D.J.* (2018) Epigenetic switch from repressive to permissive chromatin in response to cold stress. Proc. Natl. Acad. Sci. U. S. A. Cho, S., Yu, S.-i., Park, J., Mao, Y., Zhu, J.-K., Yun, D.-J., and Lee, B.-h. (2017). Accession-Dependent CBF gene deletion by CRISPR/Cas system in Arabidopsis. Front. Plant Sci. 8: 1910. Chaabane, S.B., Liu, R., Chinnusamy, V., Kwon, Y., Park, J.-h., Kim, S.Y., Zhu, J.-K., Yang, S.W.*, Lee, B.-h.* (2013) STA1, an Arabidopsis pre-mRNA processing factor 6 homolog, is a new player involved in miRNA biogenesis. Nucleic Acids Research 41: 1984-1997. | ||
| Jeong kug Lee, Ph.D. | |
Office: R207 / Phone: +82-2-705-8459 / E-Mail: jgklee@sogang.ac.kr | ||
Microbial Biomolecule Research Laboratory MORE > | ||
Research Interests | ||
Bioenergy production by microorganisms Oxidative stress defense in microorganisms Structural and functional characterization of proteins with novel functions | ||
Selected Publications | ||
Kim JS, Choi SH, Lee JK. Lysine decarboxylase expression of Vibrio vulnificus is induced by SoxR in response to superoxide stress. J Bacteriol. (2006)188: 8586-8592. Rhee HJ, Kim EJ, Lee JK. Physiological polyamines: simple primordial stress molecules. J. Cell. Mol. Med. (2007)11: 685-703. Kim EJ, Kim JS, Lee IH, Rhee HJ, Lee JK. Superoxide generation by chlorophyllide a reductase of Rhodobacter sphaeroides. J. Biol. Chem. (2008) 283: 3718-3730. | ||
| Jung-Ha Lee, Ph.D. | |
Office: R1119 / Phone: +82-2-705-8791 / E-Mail: jhleem@sogang.ac.kr | ||
Animal Physiology Laboratory MORE > | ||
Research Interests | ||
Neurophysiolgy Electrophysiology Ion channels Neural excitability | ||
Selected Publications | ||
Lee, N, Jeong, S, Kim, KC, Kim, JA, Park, JY, Kang, HW, Perez-Reyes, E, and Lee J.-H. (2017) Ca2+ Regulation of Cav3.3 T-type Ca2+ Channel Is Mediated by Calmodulin. Molecular Pharmacology 92:347-357. doi: 10.1124/mol.117.108530.
Park, SJ, Min, SH, Kang, HW, and Lee, J.-H. (2015) Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3. Biochim. Biophys. Acta.– biomembranes 1848: 2092-2100. Seo, H., Li, H.Y., Perez-Reyes, E., Lee, J.-H. (2013) Effects of Eugenol on T-type Ca2+ Channel Isoforms. J. Pharmacol. Exp. Ther. 342:310-317. | ||
| Kwang-Hwan Jung, Ph.D. | |
Office: R1203 / Phone: +82-2-705-8795 / E-Mail: kjung@sogang.ac.kr | ||
Protein Biochemistry Laboratory MORE > | ||
Research Interests | ||
Photosensory Receptor & Signal Transduction Photo-Energy Conversion & Optical Switch | ||
Selected Publications | ||
Tsogbadrakh O, Choi AR, Jung KH. (2018) Expression of Anabaena sensory rhodopsin is influenced by different codons of seven residues at the N-terminal region. Protein Expr. Purif. (IF:1.338)
Lee KY, Park S-J, Lee KA, Kim S-H, Kim H, Meroz Y, Mahadevan L, Jung KH, Ahn TK, Parker KK, Shin K. (2018) Photosynthetic artificial organelles sustain and control ATP-dependent reactions in a photocellular system. Nature Biotechnology. (IF:41.667) (co-corresponding author)
Wang C, Lee KA, Choi E, Lee KY, Lee SY, Jung KH, Park J. (2018) Enhancement of radionuclide bio-decontamination by screening highly efficient microalgae for Sr biomineralization. Lab Chip. (IF:5.995) (co-corresponding author) | ||
| Bong-Gun Ju, Ph.D. | |
Office: R213 / Phone: +82-2-705-8455 / E-Mail: bgju@sogang.ac.kr | ||
Cell Differentiation Laboratory | ||
Research Interests | ||
Stem Cell Differentiation DNA damage Response Cancer Biology | ||
Selected Publications | ||
Lunyak VV, Prefontaine GG, Nunez E, Cramer T, Ju BG, Ohgi KA, Hutt K, Roy R, Garcia-Diaz A, Zhu X, Yung Y, Montoliu L, Glass CK, Rosenfeld MG. Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science (2007) 317: 248-251 Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG. A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science (2006) 312:1798-1802 | ||
| Ching Tack Han, Ph.D. | |
Office: R1211 / Phone: +82-2-705-8458 / E-Mail: cthan@sogang.ac.kr | ||
Cellular Biochemistry Research Laboratory MORE > | ||
Research Interests | ||
Heat shock response in C. elegance | ||
Selected Publications | ||
Kim SJ, Yune TY, Han CT, Kim YC, Oh YJ, Markelonis GJ, Oh TH. Mitochondrial isocitrate dehydrogenase protects human neuroblastoma SH-SY5Y cells against oxidative stress. J. Neurosci Res. (2007) 85:139-152 Son WY, Han CT, Lee JH, Jung KY, Lee HM, Choo YK. Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice. Dev Growth Differ. (2002) 44:181-90. | ||
| Hosuk Sean Lee, Ph.D. | |
Office: K233 / Phone: / +82-2-3274-4894 / E-Mail: hslee@sogang.ac.kr | ||
Research Interests | ||
Molecular Neurobiology | ||
Selected Publications | ||
Lee HS, Ghetti A, Pinto-Duarte A, Wang X, Dziewczapolski G, Galimi F, Huitron-Resendiz S, Pina-Crespo JC, Roberts AJ, Verma IM, Sejnowski TJ, and Heinemann SF. Astrocytes contribute to gamma oscillations and recognition memory. PNAS (2014) 111(32) E3343-E3352; | ||
